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Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiologica l roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction... Less

Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular... Less

gap Boys Accessories Roomy interior, fits standard school books and binders. Colorblock detailing with bright neon trim throughout. Adjustable padded straps. Zip compartments. Embroidered logo patch at front. Interior name tag label. Assorted prints. 11.5W x 17H x 6D. Body: 100% Cotton Interior Lining: 100% Polyester

gap Womens Legging Jeans Our 100% stretch denim leggings have an unbelievable, body hugging fit that won't lose their shape with wear (we promise!). Since the fabric has such an amazing, stretchy quality, we've sized our leggings S M L. Fabrication: Lightweight, super stretchy premium denim. Wash: Black with a subtle worn in look. Hardware: Button closure, zip fly. Features: Five pocket styling. Cut: Mid rise. Fit: Skinny through the hip and thigh. Leg opening: Skinny. Inseam: 31 Sizing: Small24 26, Medium27 29, Large30 32

gap Womens Jeans Indigo wash with whickering and faded accents. Premium stretch denim. Five pocket styling with faux fly. Full panel stretches over your belly for maximum support. The nude hue is a discreet solution for lightweight or lightly colored tops. Skinny through the hip and thigh. Skinny leg opening with a shorter length. Inseams: regular: 28, long: 30, ankle: 26 Belly Panel: 92% Nylon 7% Elastane 1% Polyestyerne

gap Womens Dresses & Skirts Sleeveless. V neckline. Elasticized empire waist. Fully lined. Allover tie dye style print. Straight silhouette with an easy, relaxed fit. Hits just above the knees. Wash And Dry With Like Colors Do Not Iron Do Not Dry Clean Only Non Chlorine Bleach When Needed Tumble Dry Low Exclusive Of Decoration

gap Womens Dress Pants Introducing our really skinny. Taking a cue from our supremely stylish skinny jean, this is our sleekest and sexiest pant. The perfect dose of stretch combined with a super slim, fitted silhouette make this ultra trendy pair a true knockout.,Petite Fit Guide,Tall Fit Guide Hook & bar closure, zip fly. Back yoke. Sits below the waist. Skinny through the hip and thigh. Slim leg opening. Inseams: ankle: 29, regular: 32, long: 34, tall: 36, petite: 29

gap Men Easy So comfortable, you'll want to wear 'em everywhere. Explore our 1969 denim boutique for fit facts, fabric notes, style tips, and more. Fabrication: Premium denim. Wash: Dark rinse. Hardware: Button closure. Features: Five pocket styling. Cut: Sits at the waist. Fit: Relaxed through the leg. Leg opening: Straight leg opening.

gap Womens Jeans Clean white wash. Premium stretch denim. All around stretch panel provides support at every stage. Five pocket styling with faux fly. Demi panel sits low on your belly. The nude hue is a discreet solution for lightweight or lightly colored tops. Skinny through the hip and thigh. Slim leg opening. Inseams: regular: 28, long: 30, ankle: 25

gap Womens Curvy Petite Fit Guide,Tall Fit Guide Fabrication: Premium stretch denim. Wash: Clean rinse. Hardware: Button closure, zip fly. Features: Five pocket styling. Care: To preserve this authentic color and prevent dye from rubbing off onto other fabrics, wash inside out in cold water before wearing. Cut: Low rise. Fit: Curvy through the hip and thigh to sculpt your shape. Leg opening: Boot cut. Inseams: regular: 33, tall: 37, petite: 31